Paraoxonase 1 Polymorphism p.Q192R in Patients With Dementia
نویسندگان
چکیده
منابع مشابه
Investigating paraoxonase-1 gene Q192R and L55M polymorphism in patients with renal cell cancer.
Increased oxidative stress can help promote carcinogenesis, including development of renal cell carcinoma. The enzyme protects low-density lipoproteins from oxidation and can be a factor in this process. PON1 Q192R and L55M paraoxonase gene polymorphisms were assessed in 60 renal cell carcinoma patients and 60 healthy controls. Genotypes were examined by PCR; the restriction enzyme AlwI was use...
متن کاملparaoxonase 1 phenotype and paraoxonase activity in asthmatic patients.
oxidative stress is involved in the pathogenesis of asthma. paraoxonase 1 (pon1) and arylesterase are esterase enzymes displaying antioxidant characteristics. pon1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms. the aim of this study was to determine the activities of pon1 and arylesterase including the phenotype distribution of pon1 in asthmatic pat...
متن کاملSerum Paraoxonase 1 Activity in Patients with Organophosphate Poisoning: A Potential Indicator of Prognosis
Background: Human serum paraoxonase 1 (PON1) hydrolyzes organophosphate (OP) compounds and so significantly alters an individual’s susceptibility to the toxicity of these chemicals. The study was designed to assess the serum PON1 activity in a series of patients with OP poisoning. Methods: Suspected OP poisoning patients presented within 6 hours of...
متن کاملParaoxonase 1 phenotype and paraoxonase activity in asthmatic patients.
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics. PON1 activity varies widely among individuals and ethnic groups, partly related to polymorphisms. The aim of this study was to determine the activities of PON1 and arylesterase including the phenotype distribution of PON1 in asthmatic pat...
متن کاملFrequency of Human Paraoxonase-1 Q192R Polymorphism and Measurement of Oxidative Stress Parameters in Infants with G6PD Deficiency
Background and Aims: This study aimed to investigate the frequency of Q192R polymorphism and oxidative stress markers in infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Materials and Methods: This is a case-control study in which 60 male infants (2-4 months old) with G6PD deficiency along with 60 age- and sex-matched healthy neonates were included. The diagnosis of G6PD defic...
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2011
ISSN: 1756-0357
DOI: 10.1038/npre.2011.6333.1